Fenbendazole is a benzimidazole carbamate drug used as a broad-spectrum anthelmintic. It has been safely used as a dewormer in people and animals for six decades.
It has recently been shown to significantly inhibit the growth of cancer cells in laboratory mice. It also does not generate resistance, which is common with many other anti-cancer drugs.
How it works
Fenbendazole is a broad-spectrum anthelmintic that works well for gastrointestinal parasites such as giardia, roundworms, hookworms and pinworms. It is also used to treat tapeworms in humans. It is an antiparasitic drug in the benzimidazole family and acts by blocking the synthesis of microtubules.
In laboratory mice, fenbendazole suppressed the growth of tumors. It can be used alone or in combination with surgery, radiation, chemotherapy, or prevention. It may even make other treatments more effective.
One of the most interesting characteristics of fenbendazole is that cancer cells cannot acquire resistance to it. This is because fenbendazole does not inhibit the activity of P-glycoproteins. P-glycoproteins are important for excreting anti-cancer drugs from the cells.
The protocol for taking fenbendazole is very simple: One packet of powder per day with four days off between doses. This can be mixed with water or juice. This dosage is low enough to not cause a herxheimer reaction, although many people experience mild symptoms of detoxification.
Dosage
Mebendazole is a broad-spectrum benzimidazole carbamate anthelmintic that has been used in human and animal medicine for many years. It is most often prescribed to treat tapeworms, and may also be used to help with a few other parasitic conditions.
Mebendazole inhibits the polymerization of tubulin dimers in parasite cells and results in their death. Similarly, it inhibits glucose uptake in malignant cells, and blocks the Warburg effect. The latter means that cancer cells metabolize sugar 200 times more quickly than normal cells, and thus produce radioactive carbon ions that can be detected on PET scans.
Johns Hopkins researchers began researching fenbendazole in 2014 after accidentally discovering that it stopped glioblastoma tumors from growing on some mice in their laboratory. The drug interrupts cancer cells’ ability to process sugar and starves them of the energy they need to survive. It’s one of the four things in Joe Tippens’ protocol that he claims cured his stage IV cancer.
Side effects
Fenbendazole is a common drug used for parasite and worm treatments in animals. It kills hookworms, roundworms, whipworms, and tapeworms. It also destroys some types of protozoa and prevents them from multiplying.
It’s also being studied in humans as a potential cancer treatment. It blocks cancer cells from absorbing glucose, which they need to survive. Researchers say that the drug could be combined with other therapies, including chemotherapy and immunotherapy.
The drug does not cause side effects when used at regular doses. However, high dosages may cause vomiting and diarrhea. If this happens, seek veterinary care immediately.
Warnings
Fenbendazole is a broad-spectrum benzimidazole class anthelmintic drug that has been used in veterinary medicine to kill worms. It has also been shown in laboratory experiments to have antitumor activity against a variety of cancers.
A patient with advanced nonsmall cell lung cancer (NSCLC) self-administered oral fenbendazole, which is marketed as an antiparasitic for dogs, after receiving information about this medication from social media websites that claimed it was effective against cancer. This case report describes a patient who experienced severe liver injury after using this medication.
In a recent study, fenbendazole was found to cause cellular damage by binding to microtubules and disrupting their assembly and dynamic behavior. In addition, the drug was found to interfere with a tumor’s ability to metabolize sugar. These findings suggest that fenbendazole may be a promising treatment for some patients with cancer. However, the mechanism of action remains to be fully understood and it is not clear if it would have additional benefit as part of a comprehensive cancer therapy.sanare lab fenbendazole